Subject. Re: st: mixed effect model and autocorrelation. Date. Sat, 13 Oct 2007 12:00:33 +0200. Panel commands in Stata (note: only "S" capitalized!) usually accept unbalanced panels as input. -glamm- (remember the dashes!), which you can download from ssc (by typing: -ssc install gllamm-), allow for the option cluster, which at least partially ...we use corCAR1, which implements a continuous-time first-order autocorrelation model (i.e. autocorrelation declines exponentially with time), because we have missing values in the data. The more standard discrete-time autocorrelation models (lme offers corAR1 for a first-order model and corARMA for a more general model) don’t work with ...Apr 15, 2016 · 7. I want to specify different random effects in a model using nlme::lme (data at the bottom). The random effects are: 1) intercept and position varies over subject; 2) intercept varies over comparison. This is straightforward using lme4::lmer: lmer (rating ~ 1 + position + (1 + position | subject) + (1 | comparison), data=d) > ... May 5, 2022 · The PBmodcomp function can only be used to compare models of the same type and thus could not be used to test an LME model (Model IV) versus a linear model (Model V), an autocorrelation model (Model VIII) versus a linear model (Model V), or a mixed effects autocorrelation model (Models VI-VII) versus an autocorrelation model (Model VIII). The nlme package allows you to fit mixed effects models. So does lme4 - which is in some ways faster and more modern, but does NOT model heteroskedasticity or (!spoiler alert!) autocorrelation. Let’s try a model that looks just like our best model above, but rather than have a unique Time slope GLMMs. In principle, we simply define some kind of correlation structure on the random-effects variance-covariance matrix of the latent variables; there is not a particularly strong distinction between a correlation structure on the observation-level random effects and one on some other grouping structure (e.g., if there were a random effect of year (with multiple measurements within each year ...of freedom obtained by the same method used in the most recently fit mixed model. If option dfmethod() is not specified in the previous mixed command, option small is not allowed. For certain methods, the degrees of freedom for some linear combinations may not be available. See Small-sample inference for fixed effects in[ME] mixed for more ... Gamma mixed effects models using the Gamma() or Gamma.fam() family object. Linear mixed effects models with right and left censored data using the censored.normal() family object. Users may also specify their own log-density function for the repeated measurements response variable, and the internal algorithms will take care of the optimization. You should try many of them and keep the best model. In this case the spatial autocorrelation in considered as continous and could be approximated by a global function. Second, you could go with the package mgcv, and add a bivariate spline (spatial coordinates) to your model. This way, you could capture a spatial pattern and even map it.Jul 9, 2023 · For a linear mixed-effects model (LMM), as fit by lmer, this integral can be evaluated exactly. For a GLMM the integral must be approximated. For a GLMM the integral must be approximated. The most reliable approximation for GLMMs is adaptive Gauss-Hermite quadrature, at present implemented only for models with a single scalar random effect. Dear fellow Matlab users, Recently I have made good use of Matlab's built-in functions for making linear mixed effects. Currently I am trying to model time-series data (neuronal activity) from c...You should try many of them and keep the best model. In this case the spatial autocorrelation in considered as continous and could be approximated by a global function. Second, you could go with the package mgcv, and add a bivariate spline (spatial coordinates) to your model. This way, you could capture a spatial pattern and even map it.The nlme package allows you to fit mixed effects models. So does lme4 - which is in some ways faster and more modern, but does NOT model heteroskedasticity or (!spoiler alert!) autocorrelation. Let’s try a model that looks just like our best model above, but rather than have a unique Time slope May 5, 2022 · The PBmodcomp function can only be used to compare models of the same type and thus could not be used to test an LME model (Model IV) versus a linear model (Model V), an autocorrelation model (Model VIII) versus a linear model (Model V), or a mixed effects autocorrelation model (Models VI-VII) versus an autocorrelation model (Model VIII). Linear mixed models allow for modeling fixed, random and repeated effects in analysis of variance models. “Factor effects are either fixed or random depending on how levels of factors that appear in the study are selected. An effect is called fixed if the levels in the study represent all possible levels of theApr 11, 2023 · Inspecting and modeling residual autocorrelation with gaps in linear mixed effects models. Here I generate a dataset where measurements of response variable y and covariates x1 and x2 are collected on 30 individuals through time. Each individual is denoted by a unique ID . Apr 11, 2023 · Inspecting and modeling residual autocorrelation with gaps in linear mixed effects models. Here I generate a dataset where measurements of response variable y and covariates x1 and x2 are collected on 30 individuals through time. Each individual is denoted by a unique ID . Subject. Re: st: mixed effect model and autocorrelation. Date. Sat, 13 Oct 2007 12:00:33 +0200. Panel commands in Stata (note: only "S" capitalized!) usually accept unbalanced panels as input. -glamm- (remember the dashes!), which you can download from ssc (by typing: -ssc install gllamm-), allow for the option cluster, which at least partially ...the mixed-effect model with a first-order autocorrelation structure. The model was estimated using the R package nlme and the lme function (Pinheiro et al., 2020 ).Growth curve models (possibly Latent GCM) Mixed effects models. 이 모두는 mixed model 의 다른 종류를 말한다. 어떤 용어들은 역사가 깊고, 어떤 것들은 특수 분야에서 자주 사용되고, 어떤 것들은 특정 데이터 구조를 뜻하고, 어떤 것들은 특수한 케이스들이다. Mixed effects 혹은 mixed ... Subject. Re: st: mixed effect model and autocorrelation. Date. Sat, 13 Oct 2007 12:00:33 +0200. Panel commands in Stata (note: only "S" capitalized!) usually accept unbalanced panels as input. -glamm- (remember the dashes!), which you can download from ssc (by typing: -ssc install gllamm-), allow for the option cluster, which at least partially ...Subject. Re: st: mixed effect model and autocorrelation. Date. Sat, 13 Oct 2007 12:00:33 +0200. Panel commands in Stata (note: only "S" capitalized!) usually accept unbalanced panels as input. -glamm- (remember the dashes!), which you can download from ssc (by typing: -ssc install gllamm-), allow for the option cluster, which at least partially ...The “random effects model” (also known as the mixed effects model) is used when the analysis must account for both fixed and random effects in the model. This occurs when data for a subject are independent observations following a linear model or GLM, but the regression coefficients vary from person to person. Infant growth is aMixed Models, i.e. models with both fixed and random effects arise in a variety of research situations. Split plots, strip plots, repeated measures, multi-site clinical trials, hierar chical linear models, random coefficients, analysis of covariance are all special cases of the mixed model. Your second model is a random-slopes model; it allows for random variation in the individual-level slopes (and in the intercept, and a correlation between slopes and intercepts) m2 <- update(m1, random = ~ minutes|ID) I'd suggest the random-slopes model is more appropriate (see e.g. Schielzeth and Forstmeier 2009). Some other considerations: Aug 14, 2021 · the mixed-effect model with a first-order autocorrelation structure. The model was estimated using the R package nlme and the lme function (Pinheiro et al., 2020 ). You need to separately specify the intercept, the random effects, the model matrix, and the spde. The thing to remember is that the components of part 2 of the stack (multiplication factors) are related to the components of part 3 (the effects). Adding an effect necessitates adding another 1 to the multiplication factors (in the right place).spaMM fits mixed-effect models and allow the inclusion of spatial effect in different forms (Matern, Interpolated Markov Random Fields, CAR / AR1) but also provide interesting other features such as non-gaussian random effects or autocorrelated random coefficient (ie group-specific spatial dependency). spaMM uses a syntax close to the one used ...Eight models were estimated in which subjects nervousness values were regressed on all aforementioned predictors. The first model was a standard mixed-effects model with random effects for the intercept and the slope but no autocorrelation (Model 1 in Tables 2 and 3). The second model included such an autocorrelation (Model 2).I am seeking advice on how to effectively eliminate autocorrelation from a linear mixed model. My experimental design and explanation of fixed and random factors can be found here from an earlier question I asked: Crossed fixed effects model specification including nesting and repeated measures using glmm in ROct 31, 2016 · I'm trying to model the evolution in time of one weed species (E. crus galli) within 4 different cropping systems (=treatment). I have 5 years of data spaced out equally in time and two repetitions (block) for each cropping system. Hence, block is a random factor. Measures were repeated each year on the same block (--> repeated measure mixed ... Growth curve models (possibly Latent GCM) Mixed effects models. 이 모두는 mixed model 의 다른 종류를 말한다. 어떤 용어들은 역사가 깊고, 어떤 것들은 특수 분야에서 자주 사용되고, 어떤 것들은 특정 데이터 구조를 뜻하고, 어떤 것들은 특수한 케이스들이다. Mixed effects 혹은 mixed ...Chapter 10 Mixed Effects Models. Chapter 10. Mixed Effects Models. The assumption of independent observations is often not supported and dependent data arises in a wide variety of situations. The dependency structure could be very simple such as rabbits within a litter being correlated and the litters being independent.spaMM fits mixed-effect models and allow the inclusion of spatial effect in different forms (Matern, Interpolated Markov Random Fields, CAR / AR1) but also provide interesting other features such as non-gaussian random effects or autocorrelated random coefficient (ie group-specific spatial dependency). spaMM uses a syntax close to the one used ...There is spatial autocorrelation in the data which has been identified using a variogram and Moran's I. The problem is I tried to run a lme model, with a random effect of the State that district is within: mod.cor<-lme(FLkm ~ Monsoon.Precip + Monsoon.Temp,correlation=corGaus(form=~x+y,nugget=TRUE), data=NE1, random = ~1|State)Abstract. The ‘DHARMa’ package uses a simulation-based approach to create readily interpretable scaled (quantile) residuals for fitted (generalized) linear mixed models. Currently supported are linear and generalized linear (mixed) models from ‘lme4’ (classes ‘lmerMod’, ‘glmerMod’), ‘glmmTMB’, ‘GLMMadaptive’ and ‘spaMM ...Oct 11, 2022 · The code below shows how the random effects (intercepts) of mixed models without autocorrelation terms can be extracted and plotted. However, this approach does not work when modelling autocorrelation in glmmTMB. Use reproducible example data from this question: glmmTMB with autocorrelation of irregular times Nov 10, 2018 · You should try many of them and keep the best model. In this case the spatial autocorrelation in considered as continous and could be approximated by a global function. Second, you could go with the package mgcv, and add a bivariate spline (spatial coordinates) to your model. This way, you could capture a spatial pattern and even map it. The “random effects model” (also known as the mixed effects model) is used when the analysis must account for both fixed and random effects in the model. This occurs when data for a subject are independent observations following a linear model or GLM, but the regression coefficients vary from person to person. Infant growth is a There is spatial autocorrelation in the data which has been identified using a variogram and Moran's I. The problem is I tried to run a lme model, with a random effect of the State that district is within: mod.cor<-lme(FLkm ~ Monsoon.Precip + Monsoon.Temp,correlation=corGaus(form=~x+y,nugget=TRUE), data=NE1, random = ~1|State)6 Linear mixed-effects models with one random factor. 6.1 Learning objectives; 6.2 When, and why, would you want to replace conventional analyses with linear mixed-effects modeling? 6.3 Example: Independent-samples \(t\)-test on multi-level data. 6.3.1 When is a random-intercepts model appropriate?This is what we refer to as “random factors” and so we arrive at mixed effects models. Ta-daa! 6. Mixed effects models. A mixed model is a good choice here: it will allow us to use all the data we have (higher sample size) and account for the correlations between data coming from the sites and mountain ranges. A Lasso and a Regression Tree Mixed-Effect Model with Random Effects for the Level, the Residual Variance, and the Autocorrelation. Research in psychology is experiencing a rapid increase in the availability of intensive longitudinal data.Eight models were estimated in which subjects nervousness values were regressed on all aforementioned predictors. The first model was a standard mixed-effects model with random effects for the intercept and the slope but no autocorrelation (Model 1 in Tables 2 and 3). The second model included such an autocorrelation (Model 2). in nlme, it is possible to specify the variance-covariance matrix for the random effects (e.g. an AR (1)); it is not possible in lme4. Now, lme4 can easily handle very huge number of random effects (hence, number of individuals in a given study) thanks to its C part and the use of sparse matrices. The nlme package has somewhat been superseded ...What is autocorrelation? Generalized Additive Mixed Effects Models have several components: Smooth terms for covariates; Random Effects: Intercepts, Slopes and Smooths. Categorical Predictors; Interactions of (1)-(3) We can add one more component for autocorrelation: modeling the residuals: Covariance structure for the residuals. Growth curve models (possibly Latent GCM) Mixed effects models. 이 모두는 mixed model 의 다른 종류를 말한다. 어떤 용어들은 역사가 깊고, 어떤 것들은 특수 분야에서 자주 사용되고, 어떤 것들은 특정 데이터 구조를 뜻하고, 어떤 것들은 특수한 케이스들이다. Mixed effects 혹은 mixed ...To do this, you would specify: m2 <- lmer (Obs ~ Day + Treatment + Day:Treatment + (Day | Subject), mydata) In this model: The intercept if the predicted score for the treatment reference category at Day=0. The coefficient for Day is the predicted change over time for each 1-unit increase in days for the treatment reference category. What is autocorrelation? Generalized Additive Mixed Effects Models have several components: Smooth terms for covariates; Random Effects: Intercepts, Slopes and Smooths. Categorical Predictors; Interactions of (1)-(3) We can add one more component for autocorrelation: modeling the residuals: Covariance structure for the residuals. Sep 16, 2018 · Recently I have made good use of Matlab's built-in functions for making linear mixed effects. Currently I am trying to model time-series data (neuronal activity) from cognitive experiments with the fitlme() function using two continuous fixed effects (linear speed and acceleration) and several, hierarchically nested categorical random factors (subject identity, experimental session and binned ... To use such data for predicting feelings, beliefs, and behavior, recent methodological work suggested combinations of the longitudinal mixed-effect model with Lasso regression or with regressi … A Lasso and a Regression Tree Mixed-Effect Model with Random Effects for the Level, the Residual Variance, and the Autocorrelation c (Claudia Czado, TU Munich) – 11 – Likelihood Inference for LMM: 1) Estimation of β and γ for known G and R Estimation of β: Using (5), we have as MLE or weighted LSE of β Random intercept + Autocorrelation structure on the errors, and; Autocorrelation structure on the errors only (using gls() command). I fit model 3 because I've been taught that sometimes an autocorrelation structure is enough for longitudinal data. For model 1, variance of random effect (intercept) was 676.9 (and accounted for 62% of total ...a random effect for the autocorrelation. After introducing the extended mixed-effect location scale (E-MELS), ... mixed-effect models that have been, for example, combined with Lasso regression (e ...Sep 22, 2015 · $\begingroup$ it's more a please check that I have taken care of the random effects, autocorrelation, and a variance that increases with the mean properly. $\endgroup$ – M.T.West Sep 22, 2015 at 12:15 The nlme package allows you to fit mixed effects models. So does lme4 - which is in some ways faster and more modern, but does NOT model heteroskedasticity or (!spoiler alert!) autocorrelation. Let’s try a model that looks just like our best model above, but rather than have a unique Time slope The nlme package allows you to fit mixed effects models. So does lme4 - which is in some ways faster and more modern, but does NOT model heteroskedasticity or (!spoiler alert!) autocorrelation. Let’s try a model that looks just like our best model above, but rather than have a unique Time slope Sep 16, 2018 · Recently I have made good use of Matlab's built-in functions for making linear mixed effects. Currently I am trying to model time-series data (neuronal activity) from cognitive experiments with the fitlme() function using two continuous fixed effects (linear speed and acceleration) and several, hierarchically nested categorical random factors (subject identity, experimental session and binned ... The “random effects model” (also known as the mixed effects model) is used when the analysis must account for both fixed and random effects in the model. This occurs when data for a subject are independent observations following a linear model or GLM, but the regression coefficients vary from person to person. Infant growth is a the mixed-effect model with a first-order autocorrelation structure. The model was estimated using the R package nlme and the lme function (Pinheiro et al., 2020 ).Your second model is a random-slopes model; it allows for random variation in the individual-level slopes (and in the intercept, and a correlation between slopes and intercepts) m2 <- update(m1, random = ~ minutes|ID) I'd suggest the random-slopes model is more appropriate (see e.g. Schielzeth and Forstmeier 2009). Some other considerations:Dec 24, 2014 · Is it accurate to say that we used a linear mixed model to account for missing data (i.e. non-response; technology issues) and participant-level effects (i.e. how frequently each participant used ... Eight models were estimated in which subjects nervousness values were regressed on all aforementioned predictors. The first model was a standard mixed-effects model with random effects for the intercept and the slope but no autocorrelation (Model 1 in Tables 2 and 3). The second model included such an autocorrelation (Model 2). Models all contained the same fixed effects, were compared using AIC, and were fitted by REML (to allow comparison of different correlation structures by AIC). I'm using the R package nlme and the gls function. Question 1. The GLS models' residuals still display almost identical cyclical patterns when plotted against time.Eight models were estimated in which subjects nervousness values were regressed on all aforementioned predictors. The first model was a standard mixed-effects model with random effects for the intercept and the slope but no autocorrelation (Model 1 in Tables 2 and 3). The second model included such an autocorrelation (Model 2).The following simulates and fits a model where the linear predictor in the logistic regression follows a zero-mean AR(1) process, see the glmmTMB package vignette for more details.Growth curve models (possibly Latent GCM) Mixed effects models. 이 모두는 mixed model 의 다른 종류를 말한다. 어떤 용어들은 역사가 깊고, 어떤 것들은 특수 분야에서 자주 사용되고, 어떤 것들은 특정 데이터 구조를 뜻하고, 어떤 것들은 특수한 케이스들이다. Mixed effects 혹은 mixed ... the mixed-effect model with a first-order autocorrelation structure. The model was estimated using the R package nlme and the lme function (Pinheiro et al., 2020 ).Nov 1, 2019 · Therefore, even greater sampling rates will be required when autocorrelation is present to meet the levels prescribed by analyses of the power and precision when estimating individual variation using mixed effect models (e.g., Wolak et al. 2012; Dingemanse and Dochtermann 2013) Zuur et al. in \"Mixed Effects Models and Extensions in Ecology with R\" makes the point that fitting any temporal autocorrelation structure is usually far more important than getting the perfect structure. Start with AR1 and try more complicated structures if that seems insufficient. A random effects model that contains only random intercepts, which is the most common use of mixed effect modeling in randomized trials, assumes that the responses within subject are exchangeable. This can be seen from the statement of the linear mixed effects model with random intercepts.A Lasso and a Regression Tree Mixed-Effect Model with Random Effects for the Level, the Residual Variance, and the Autocorrelation. Research in psychology is experiencing a rapid increase in the availability of intensive longitudinal data.Abstract. The ‘DHARMa’ package uses a simulation-based approach to create readily interpretable scaled (quantile) residuals for fitted (generalized) linear mixed models. Currently supported are linear and generalized linear (mixed) models from ‘lme4’ (classes ‘lmerMod’, ‘glmerMod’), ‘glmmTMB’, ‘GLMMadaptive’ and ‘spaMM ...1 discussing the implicit correlation structure that is imposed by a particular model. This is easiest seen in repeated measures. The simplest model with occasions nested in individuals with a ...c (Claudia Czado, TU Munich) – 11 – Likelihood Inference for LMM: 1) Estimation of β and γ for known G and R Estimation of β: Using (5), we have as MLE or weighted LSE of βwe use corCAR1, which implements a continuous-time first-order autocorrelation model (i.e. autocorrelation declines exponentially with time), because we have missing values in the data. The more standard discrete-time autocorrelation models (lme offers corAR1 for a first-order model and corARMA for a more general model) don’t work with ...a random effect for the autocorrelation. After introducing the extended mixed-effect location scale (E-MELS), ... mixed-effect models that have been, for example, combined with Lasso regression (e ...It is evident that the classical bootstrap methods developed for simple linear models should be modified to take into account the characteristics of mixed-effects models (Das and Krishen 1999). In ...Zuur et al. in \"Mixed Effects Models and Extensions in Ecology with R\" makes the point that fitting any temporal autocorrelation structure is usually far more important than getting the perfect structure. Start with AR1 and try more complicated structures if that seems insufficient. 7. I want to specify different random effects in a model using nlme::lme (data at the bottom). The random effects are: 1) intercept and position varies over subject; 2) intercept varies over comparison. This is straightforward using lme4::lmer: lmer (rating ~ 1 + position + (1 + position | subject) + (1 | comparison), data=d) > ...PROC MIXED in the SAS System provides a very flexible modeling environment for handling a variety of repeated measures problems. Random effects can be used to build hierarchical models correlating measurements made on the same level of a random factor, including subject-specific regression models, while a variety of covariance and It is a linear mixed model, with log-transformed OM regressed on marsh site (categorical), marsh type (categorical), soil category (categorical), depth (numerical, based on ordinal depth ranges), and the interaction between depth and marsh type; marsh site effects are modeled as random, on which the ICAR spatial autocorrelation structure is ...A comparison to mixed models. We noted previously that there were ties between generalized additive and mixed models. Aside from the identical matrix representation noted in the technical section, one of the key ideas is that the penalty parameter for the smooth coefficients reflects the ratio of the residual variance to the variance components for the random effects (see Fahrmeier et al ... Zuur et al. in \"Mixed Effects Models and Extensions in Ecology with R\" makes the point that fitting any temporal autocorrelation structure is usually far more important than getting the perfect structure. Start with AR1 and try more complicated structures if that seems insufficient. 1 Answer. Mixed models are often a good choice when you have repeated measures, such as here, within whales. lme from the nlme package can fit mixed models and also handle autocorrelation based on a AR (1) process, where values of X X at t − 1 t − 1 determine the values of X X at t t.
This is what we refer to as “random factors” and so we arrive at mixed effects models. Ta-daa! 6. Mixed effects models. A mixed model is a good choice here: it will allow us to use all the data we have (higher sample size) and account for the correlations between data coming from the sites and mountain ranges. . 5 325 mg
Abstract. The use of linear mixed effects models (LMMs) is increasingly common in the analysis of biological data. Whilst LMMs offer a flexible approach to modelling a broad range of data types, ecological data are often complex and require complex model structures, and the fitting and interpretation of such models is not always straightforward.The first model was a longitudinal mixed-effect model with a first-order autocorrelation structure, and the second model was the E-MELS. Both were implemented as described above. The third model was a longitudinal mixed-effect model with a Lasso penalty.Mixed Effects Models - Autocorrelation. Jul. 1, 2021 • 0 likes • 171 views. Download Now. Download to read offline. Education. Lecture 19 from my mixed-effects modeling course: Autocorrelation in longitudinal and time-series data. Scott Fraundorf Follow.I am seeking advice on how to effectively eliminate autocorrelation from a linear mixed model. My experimental design and explanation of fixed and random factors can be found here from an earlier question I asked: Crossed fixed effects model specification including nesting and repeated measures using glmm in R(1) this assumes the temporal pattern is the same across subjects; (2) because gamm() uses lme rather than lmer under the hood you have to specify the random effect as a separate argument. (You could also use the gamm4 package, which uses lmer under the hood.) You might want to allow for temporal autocorrelation. For example,I am seeking advice on how to effectively eliminate autocorrelation from a linear mixed model. My experimental design and explanation of fixed and random factors can be found here from an earlier question I asked: Crossed fixed effects model specification including nesting and repeated measures using glmm in RI'm trying to model the evolution in time of one weed species (E. crus galli) within 4 different cropping systems (=treatment). I have 5 years of data spaced out equally in time and two repetitions (block) for each cropping system. Hence, block is a random factor. Measures were repeated each year on the same block (--> repeated measure mixed ...a combination of both models (ARMA). random effects that model independence among observations from the same site using GAMMs. That is, in addition to changing the basis as with the nottem example, we can also add complexity to the model by incorporating an autocorrelation structure or mixed effects using the gamm() function in the mgcv package Linear Mixed Effects Models. Linear Mixed Effects models are used for regression analyses involving dependent data. Such data arise when working with longitudinal and other study designs in which multiple observations are made on each subject. Some specific linear mixed effects models are. Random intercepts models, where all responses in a ...$\begingroup$ it's more a please check that I have taken care of the random effects, autocorrelation, and a variance that increases with the mean properly. $\endgroup$ – M.T.West Sep 22, 2015 at 12:15This example will use a mixed effects model to describe the repeated measures analysis, using the lme function in the nlme package. Student is treated as a random variable in the model. The autocorrelation structure is described with the correlation statement.1 discussing the implicit correlation structure that is imposed by a particular model. This is easiest seen in repeated measures. The simplest model with occasions nested in individuals with a ...Jul 1, 2021 · Mixed Effects Models - Autocorrelation. Jul. 1, 2021 • 0 likes • 171 views. Download Now. Download to read offline. Education. Lecture 19 from my mixed-effects modeling course: Autocorrelation in longitudinal and time-series data. Scott Fraundorf Follow. Recently I have made good use of Matlab's built-in functions for making linear mixed effects. Currently I am trying to model time-series data (neuronal activity) from cognitive experiments with the fitlme() function using two continuous fixed effects (linear speed and acceleration) and several, hierarchically nested categorical random factors (subject identity, experimental session and binned ....